Research plays a central role in SANE’s work; it informs how we help people through our services, guides our campaigns and helps to ensure there is a greater variety of effective treatments. The dissemination of knowledge and increasing people's understanding of mental illness are two of SANE’s core aims, providing the essential structure for our outcomes.

Stained_GlassSANE founded the Prince of Wales International Centre (POWIC) for SANE Research in Oxford in 2003. Under the leadership of Professor Tim Crow, SANE is conducting a research programme into the yet unknown causes of schizophrenia and psychosis. The aim is to generate a knowledge base for novel and innovative treatments for these devastating conditions.

Our neuroscience researchers look for physiological causes of mental illness, specifically in psychotic conditions like schizophrenia, by studying genetics and brain chemistry.

Professor Crow says: “Together with my team we continue working on our hypothesis that psychosis including both schizophrenia and the affective psychoses is related to those distinctive aspects of the human brain which could be the best contender for explaining our faculty for language."