Hi there- I have suffered with depression on and off for years but last 2 years have used St. John's wort and lightbox with effectiveness instead of SSRIs which gave me side effects. However, my mood has dropped lately. My doctor wants me to try sertraline but I've read that 5-HTP can possibly be used with St. John's wort safely? Has anyone used both together? I'm also increasing the exercise I do. Be great if I could recover without need to go back on chemical antidepressants which would prob give me side effects again. Grateful for any feedback and information, thanks.