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SANE comment on Nice not recommending esketamine
Added: 28th Jan 2020

Please find below comment from Marjorie Wallace, chief executive of the mental health charity SANE, on the National Institute for Health and Clinical Excellence not recommending esketamine for treatment-resistant depression:

“People with depression are currently relying on medications that are 30 years old. Although these drugs can be life-saving for some people, they can have unpleasant side-effects and do not work for everyone.

“It is therefore deeply disappointing that the first new compound that works in a fundamentally different way on the brain should not have passed this hurdle.

“This is especially so because people can take as much as six to eight weeks to feel the full effects of most antidepressants, whereas esketamine effectiveness can be judged in 24 hours, potentially saving patients weeks or months of uncertainty.

“We hope this setback will serve only to inspire pharmaceutical companies, researchers and others to discover new ways of treating serious depression.”

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